PBCO has developed a resource to aid in the basic understanding of all transfusion reactions:
For a more thorough review of specific transfusion reactions check out the following transfusion reaction cards that each outline:
• Etiology of the reaction
• Signs and Symptoms
• What happens “At the Bedside”
• What happens “In the Lab” - for additional information see What Happens After TM Physician Review?
• Considerations for future transfusions (if any)
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Febrile Transfusion Reactions |
|
|
Allergic Transfusion Reactions |
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| Minor Allergic | |
| Severe/ Anaphylactic/ Anaphylactoid | IVIg Anaphylactic Shock |
|
Respiratory Transfusion Reactions |
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| TRALI (Transfusion Related Acute Lung Injury) | |
|
Other Transfusion Reactions |
|
| IVIg Aseptic Meningitis | |
Note: the above transfusion reactions only represent those which are frequently reported and do not account for all possible signs and symptoms or reactions. Similarly, the steps accounted for at the bedside, in the lab, and for future transfusions, are those that would be routine and do not account for more in-depth investigation(s) or treatment(s), which may be required in some instances.
Additional Resources:
• CBS Chapter 10: Transfusion reactions
• ORBCoN Resource Manual for Medical Directors of Transfusion Medicine: 11.0 Transfusion Reactions
• ISBT Transfusion Reactions E-learning Module
• Video: Transfusion Reaction Interactive Case Review: It’s getting HOT – let’s talk fevers (presented at the BC Transfusion Medicine Rounds, October 2023)
