C1 Esterase Inhibitor (C1EI) is a blood product that is licensed in Canada for the treatment of Hereditary Angioedema.

A provincial immunology and allergy working group, chaired by the PBCO, has endorsed the following algorithms. In addition, a sample letter is available, should an Immunologist wish to adapt and implement it for use in their practice.


Hereditary Angioedema Diagnosis Algorithm

Mar 2013

Hereditary Angioedema Treatment Recommendations

Jan 2016

Hereditary Angioedema Long Term Prophylaxis Recommendations

 Jan 2016
 Sample Letter  

Hereditary Angioedema Sample Letter for Patients (from diagnosing physician)


Dec 2015

TMS IVIG Request Process

 Other Resources on C1 Esterase Inhibitor:

 Additional Resources

2014 Canadian Hereditary Angioedema Guideline

Hereditary Angioedema Presentation